Isaiah 1:4

Alas, O sinful nation, a people laden with iniquity, a brood of evildoers, children of depravity! They have forsaken the Lord; they have despised the Holy One of Israel and turned their backs on Him.
BSB · Berean Standard Bible
Ah sinful nation, a people laden with iniquity, a seed of evildoers, children that are corrupters: they have forsaken the Lord, they have provoked the Holy One of Israel unto anger, they are gone away backward.

Note laden: Heb. of heaviness

Note gone…: Heb. alienated, or, separated

KJV · King James Version
Ah sinful nation, a people loaded with iniquity, offspring of evildoers, children who deal corruptly! They have forsaken the Lord. They have despised the Holy One of Israel. They are estranged and backward.

Note or, seed

WEB · World English Bible
Ah sinful nation, a people laden with iniquity, a seed of evil-doers, children that deal corruptly! they have forsaken Jehovah, they have despised the Holy One of Israel, they are estranged and gone backward.
ASV · American Standard Version

Related passages

From the Treasury of Scripture Knowledge, grouped by the word they explain.

Ah sinful
Isaiah 1:23; Isaiah 10:6; Isaiah 30:9; Genesis 13:13; Matthew 11:28; Acts 7:51, 52; Revelation 18:5
laden with iniquity
Heb. of heaviness. a seed.
Isaiah 57:3, 4; Numbers 32:14; Psalm 78:8; Jeremiah 7:26; Jeremiah 16:11, 12; Matthew 3:7; Matthew 23:33
children
Jeremiah 2:33; Ezekiel 16:33
forsaken
Deuteronomy 29:25; Deuteronomy 31:16; Judges 10:10; Jeremiah 2:13, 17, 19
provoked
Isaiah 3:8; Isaiah 65:3; Deuteronomy 32:19; Psalm 78:40; Jeremiah 7:19; 1 Corinthians 10:22
the Holy
Isaiah 5:19, 24; Isaiah 12:6; Isaiah 29:19; Isaiah 30:11, 12, 15; Isaiah 37:23; Isaiah 41:14, 16, 20; Psalm 89:18; Jeremiah 50:29; Jeremiah 51:5
gone away backward
Heb. alienated, or separated.
Psalm 58:3; Jeremiah 2:5, 31; Romans 8:7; Colossians 1:24